Detailed Review on Sustainable Pharmaceutics: Green Chemistry And Eco-Friendly Formulations

Abstract:

The pharmaceutical industry is under increasing pressure to adopt sustainable practices due to its significant environmental impact, particularly in terms of waste generation, energy consumption, and reliance on non-renewable resources. Sustainable pharmaceutics, integrating green chemistry principles and eco-friendly formulations, offer a pathway to reducing this environmental footprint while maintaining drug efficacy and safety. This review explores the application of green chemistry in pharmaceutical development, focusing on the use of biodegradable excipients, green solvents, and environmentally benign synthesis methods. Key green chemistry principles such as waste prevention, atom economy, and energy efficiency are discussed in relation to pharmaceutical formulations. Additionally, the review highlights innovations in biodegradable polymers, natural polysaccharides, and alternative drug delivery systems that align with sustainability goals. Case studies demonstrate the successful implementation of green processes in pharmaceutical production, such as the sustainable synthesis of aspirin and the use of biodegradable materials in controlled release systems. Despite challenges, including higher costs and regulatory barriers, the shift toward sustainable pharmaceutics presents significant opportunities for reducing the ecological impact of pharmaceutical products. The review concludes with a discussion on future directions, including the continued development of biocatalysis, circular economy models, and alternative drug delivery methods. Ultimately, sustainable pharmaceutics is positioned as a critical step toward achieving environmental sustainability in the pharmaceutical industry while continuing to meet therapeutic needs.Keywords: Pharmaceutical industry, Sustainable practices, Environmental impact, Waste generation.

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